An Ultraconserved Element Containing lncRNA Preserves Transcriptional Dynamics and Maintains ESC Self-Renewal

Ultraconserved elements (UCEs) show the peculiar feature to retain extended perfect sequence identity among human, mouse, and rat genomes. Most of them are transcribed and represent a new family of long non-coding RNAs (lncRNAs), the transcribed UCEs (T-UCEs). Despite their involvement in human canc...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Fiorenzano, Alessandro, Pascale, Emilia, Gagliardi, Miriam, Terreri, Sara, Papa, Mariarosaria, Andolfi, Gennaro, Galasso, Marco, Tagliazucchi, Guidantonio Malagoli, Taccioli, Cristian, Patriarca, Eduardo Jorge, Cimmino, Amelia, Matarazzo, Maria Rosaria, Minchiotti, Gabriella, Fico, Annalisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918197/
https://ncbi.nlm.nih.gov/pubmed/29456181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.014
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