An Assay that Predicts In Vivo Efficacy for DNA Aptamers that Stimulate Remyelination in a Mouse Model of Multiple Sclerosis

Multiple sclerosis (MS) is a debilitating disease for which regenerative therapies are sought. We have previously described human antibodies and DNA aptamer-streptavidin conjugates that promote remyelination after systemic injection into mice infected by Theiler’s murine encephalomyelitis virus. Her...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Heider, Robin M., Smestad, John A., Lemus, Hernan Nicolas, Wilbanks, Brandon, Warrington, Arthur E., Peters, Justin P., Rodriguez, Moses, Maher, L. James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918178/
https://ncbi.nlm.nih.gov/pubmed/29707601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.03.005
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