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Synergistic Effect of Cyclosporin A and Verapamil in Overcoming Vincristine Resistance of Multidrug‐resistant Cultured Human Leukemia Cells

Reversal of vincristine (VCR) resistance by cyclosporin A (CyA) or the combination of CyA and verapamil (VER) was investigated by using four P‐glycoprotein (P‐gp)‐associated human multidrug‐resistant (MDR) cell lines (K562/ADM, KYO‐1, HEL and CMK). Drug sensitivity was expressed as 50% inhibitory co...

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Bibliografische gegevens
Gepubliceerd in:Jpn J Cancer Res
Hoofdauteurs: Ishida, Yasushi, Shimada, Yasuhiro, Shimoyama, Masanori
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 1990
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918095/
https://ncbi.nlm.nih.gov/pubmed/2118896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1990.tb02653.x
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