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Synergistic Effect of Cyclosporin A and Verapamil in Overcoming Vincristine Resistance of Multidrug‐resistant Cultured Human Leukemia Cells
Reversal of vincristine (VCR) resistance by cyclosporin A (CyA) or the combination of CyA and verapamil (VER) was investigated by using four P‐glycoprotein (P‐gp)‐associated human multidrug‐resistant (MDR) cell lines (K562/ADM, KYO‐1, HEL and CMK). Drug sensitivity was expressed as 50% inhibitory co...
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| Publicat a: | Jpn J Cancer Res |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Publishing Ltd
1990
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5918095/ https://ncbi.nlm.nih.gov/pubmed/2118896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1990.tb02653.x |
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