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Mutational Activation of H‐ras and K‐ras Genes Is Absent in N‐Nitroso‐N‐methylurea‐induced Liver Tumors in Rats
We examined mutational activation of H‐ and K‐ras genes in hyperplastic nodules and hepatocellular carcinomas induced by N‐nitroso‐N‐methylurea or diethylnitrosamine using the polymerase chain reaction, followed by dot‐blot hybridization. No mutational activation was detected in these hepatic lesion...
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| Publicado no: | Jpn J Cancer Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5918065/ https://ncbi.nlm.nih.gov/pubmed/2116389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1990.tb02587.x |
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