Granulocyte‐colony Stimulating Factor and Retinoic Acid Cooperatively Induce Granulocytic Differentiation of Acute Promyelocytic Leukemia Cells in vitro

The interaction of granulocyte‐colony stimulating factor (G‐CSF) and retinoic acid (RA) in proliferation and differentiation of acute promyelocytic leukemia (APL) cells was examined. G‐CSF stimulated proliferation of APL cells at concentrations of 0.1 to 50 ng/ml in a dose dependent manner. More tha...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Nakamaki, Tsuyoshi, Sakashita, Akiko, Sano, Motoharu, Hino, Ken‐ichiro, Suzuki, Kazuo, Tomoyasu, Shigeru, Tsuruoka, Nobuyoshi, Honma, Yoshio, Hozumi, Motoo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1989
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917906/
https://ncbi.nlm.nih.gov/pubmed/2481663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1989.tb02262.x
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