Enhancement of Both Intracellular Uptake and Antitumor Action of Cisplatinum on Human Neuroblastoma Cells by Encapsulation in Liposomes

Phospholipid vesicles (phosphatidylcholine: phosphatidylserine: cholesterol=6:2:3 in molar ratio) with a small unilamellar structure were used as drug carriers for introducing cis‐diamminedichloroplatinum (CDDP) into human neuroblastoma cells, IMR‐32, GOTO, Nagai, and TGW. DNA synthesis of IMR‐32 ce...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Kamio, Yoshiro, Kato, Hiroshi, Kishikawa, Teruaki, Toda, Takashi, Sasaki, Shingi, Ito, Jin‐ichi, Kato, Taiji, Tanaka, Ryo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1989
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917833/
https://ncbi.nlm.nih.gov/pubmed/2511188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1989.tb01716.x
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