Pharmacokinetic Modulation of Plasma 5‐Fluorouracil Concentrations to Potentiate the Antitumor Activity of Continuous Venous Infusion of 5‐Fluorouracil

Methods for pharmacokinetic modulation of the plasma 5‐fluorouracil (5‐FU) level to increase antitumor activity during continuous venous infusion (CVI) of low doses of 5‐FU were examined in Yoshida sarcoma‐bearing rats. These methods were additional infusion of 5‐FU for a short period (4 h) or oral...

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Publicado en:Jpn J Cancer Res
Autores principales: Fujii, Setsuro, Fukushima, Masakazu, Shimamoto, Yuji, Shirasaka, Tetsuhiko
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 1989
Materias:
Rapid Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917802/
https://ncbi.nlm.nih.gov/pubmed/2503471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1989.tb01668.x
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