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N-Acetyl-2-Aminofluorene (AAF) Processing in Adult Rat Hepatocytes in Primary Culture Occurs by High-Affinity Low-Velocity and Low-Affinity High-Velocity AAF Metabolite-Forming Systems
N-acetyl-2-aminofluorene (AAF) is a procarcinogen used widely in physiological investigations of chemical hepatocarcinogenesis. Its metabolic pathways have been described extensively, yet little is known about its biochemical processing, growth cycle expression, and pharmacological properties inside...
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出版年: | Toxicol Sci |
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主要な著者: | , , , |
フォーマット: | Artigo |
言語: | Inglês |
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Oxford University Press
2018
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5917773/ https://ncbi.nlm.nih.gov/pubmed/29319795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy006 |
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