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N-Acetyl-2-Aminofluorene (AAF) Processing in Adult Rat Hepatocytes in Primary Culture Occurs by High-Affinity Low-Velocity and Low-Affinity High-Velocity AAF Metabolite-Forming Systems

N-acetyl-2-aminofluorene (AAF) is a procarcinogen used widely in physiological investigations of chemical hepatocarcinogenesis. Its metabolic pathways have been described extensively, yet little is known about its biochemical processing, growth cycle expression, and pharmacological properties inside...

詳細記述

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書誌詳細
出版年:Toxicol Sci
主要な著者: Koch, Katherine S, Moran, Tom, Shier, W Thomas, Leffert, Hyam L
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917773/
https://ncbi.nlm.nih.gov/pubmed/29319795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy006
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