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DNA Alkylation by Nitrosobis‐(2‐oxopropyl) amine in Rats of Different Ages

We have examined the methylation of liver DNA (O(6)‐ and N(7)‐methylguanine) by nitrosobis‐(2‐oxopropyl)amine (BOP) in male and female rats at various ages, following treatment with 2.5 mg of BOP; this dose given twice weekly for 30 weeks induces tumors in all animals. Except in young rats there was...

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Bibliografische gegevens
Gepubliceerd in:Jpn J Cancer Res
Hoofdauteurs: Lhomas, Barbara J., Lijinsky, William
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 1988
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917622/
https://ncbi.nlm.nih.gov/pubmed/3142834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1988.tb00071.x
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