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DNA Alkylation by Nitrosobis‐(2‐oxopropyl) amine in Rats of Different Ages
We have examined the methylation of liver DNA (O(6)‐ and N(7)‐methylguanine) by nitrosobis‐(2‐oxopropyl)amine (BOP) in male and female rats at various ages, following treatment with 2.5 mg of BOP; this dose given twice weekly for 30 weeks induces tumors in all animals. Except in young rats there was...
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| Publicado no: | Jpn J Cancer Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5917622/ https://ncbi.nlm.nih.gov/pubmed/3142834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1988.tb00071.x |
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