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Using Protein Homology Models for Structure-Based Studies: Approaches to Model Refinement

Homology modeling is a computational methodology to assign a 3-D structure to a target protein when experimental data are not available. The methodology uses another protein with a known structure that shares some sequence identity with the target as a template. The crudest approach is to thread the...

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Bibliografske podrobnosti
izdano v:ScientificWorldJournal
Main Authors: Kairys, V., Gilson, M.K., Fernandes, Miguel Xavier
Format: Artigo
Jezik:Inglês
Izdano: TheScientificWorldJOURNAL 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917253/
https://ncbi.nlm.nih.gov/pubmed/17160340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2006.250
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