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Building and Refining Protein Models within Cryo-electron Microscopy Density Maps Based on Homology Modeling and Multi-scale Structure Refinement

Automatic modeling methods using cryo-electron microscopy (cryoEM) density maps as constrains are promising approaches to building atomic models of individual proteins or protein domains. However, their application to large macromolecular assemblies has not been possible largely due to computational...

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Hlavní autoři: Zhu, Jiang, Cheng, Lingpeng, Fang, Qin, Hong Zhou, Z., Honig, Barry
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860449/
https://ncbi.nlm.nih.gov/pubmed/20109465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.041
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