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Building and Refining Protein Models within Cryo-electron Microscopy Density Maps Based on Homology Modeling and Multi-scale Structure Refinement

Automatic modeling methods using cryo-electron microscopy (cryoEM) density maps as constrains are promising approaches to building atomic models of individual proteins or protein domains. However, their application to large macromolecular assemblies has not been possible largely due to computational...

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Detalhes bibliográficos
Main Authors: Zhu, Jiang, Cheng, Lingpeng, Fang, Qin, Hong Zhou, Z., Honig, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860449/
https://ncbi.nlm.nih.gov/pubmed/20109465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.041
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