Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply

Transplantation of encapsulated islets can cure diabetes without immunosuppression, but oxygen supply limitations can cause failure. We investigated a retrievable macroencapsulation device wherein islets are encapsulated in a planar alginate slab and supplied with exogenous oxygen from a replenishab...

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Pubblicato in:Sci Rep
Autori principali: Evron, Yoav, Colton, Clark K., Ludwig, Barbara, Weir, Gordon C., Zimermann, Baruch, Maimon, Shiri, Neufeld, Tova, Shalev, Nurit, Goldman, Tali, Leon, Assaf, Yavriyants, Karina, Shabtay, Noa, Rozenshtein, Tania, Azarov, Dimitri, DiIenno, Amanda R., Steffen, Anja, de Vos, Paul, Bornstein, Stefan R., Barkai, Uriel, Rotem, Avi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917036/
https://ncbi.nlm.nih.gov/pubmed/29695723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23862-w
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