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Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply

Transplantation of encapsulated islets can cure diabetes without immunosuppression, but oxygen supply limitations can cause failure. We investigated a retrievable macroencapsulation device wherein islets are encapsulated in a planar alginate slab and supplied with exogenous oxygen from a replenishab...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Evron, Yoav, Colton, Clark K., Ludwig, Barbara, Weir, Gordon C., Zimermann, Baruch, Maimon, Shiri, Neufeld, Tova, Shalev, Nurit, Goldman, Tali, Leon, Assaf, Yavriyants, Karina, Shabtay, Noa, Rozenshtein, Tania, Azarov, Dimitri, DiIenno, Amanda R., Steffen, Anja, de Vos, Paul, Bornstein, Stefan R., Barkai, Uriel, Rotem, Avi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917036/
https://ncbi.nlm.nih.gov/pubmed/29695723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23862-w
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