Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply

Transplantation of encapsulated islets can cure diabetes without immunosuppression, but oxygen supply limitations can cause failure. We investigated a retrievable macroencapsulation device wherein islets are encapsulated in a planar alginate slab and supplied with exogenous oxygen from a replenishab...

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Foilsithe in:Sci Rep
Main Authors: Evron, Yoav, Colton, Clark K., Ludwig, Barbara, Weir, Gordon C., Zimermann, Baruch, Maimon, Shiri, Neufeld, Tova, Shalev, Nurit, Goldman, Tali, Leon, Assaf, Yavriyants, Karina, Shabtay, Noa, Rozenshtein, Tania, Azarov, Dimitri, DiIenno, Amanda R., Steffen, Anja, de Vos, Paul, Bornstein, Stefan R., Barkai, Uriel, Rotem, Avi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917036/
https://ncbi.nlm.nih.gov/pubmed/29695723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23862-w
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