Targeting of glutamine transporter ASCT2 and glutamine synthetase suppresses gastric cancer cell growth

PURPOSE: Glutamine (Gln) is essential for the proliferation of most cancer cells, making it an appealing target for cancer therapy. However, the role of Gln in gastric cancer (GC) metabolism is unknown and Gln-targeted therapy against GC remains scarce. The aim of this study was to investigate the r...

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I publikationen:J Cancer Res Clin Oncol
Huvudupphovsmän: Ye, Jianxin, Huang, Qiang, Xu, Jie, Huang, Jinsheng, Wang, Jinzhou, Zhong, Wenjing, Chen, Wannan, Lin, Xinjian, Lin, Xu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2018
Ämnen:
Original Article – Cancer Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916984/
https://ncbi.nlm.nih.gov/pubmed/29435734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-018-2605-9
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