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Experimental autoimmune encephalomyelitis (EAE) up-regulates the mitochondrial activity and manganese superoxide dismutase (MnSOD) in the mouse renal cortex

Increases of the activity of mitochondrial electron transport chain generally lead to increases of production of ATP and reactive oxygen species (ROS) as by-products. MnSOD is the first line of defense against the stress induced by mitochondrial ROS. Our previous studies demonstrated that EAE progre...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Packialakshmi, Balamurugan, Zhou, Xiaoming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916489/
https://ncbi.nlm.nih.gov/pubmed/29689072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196277
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