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Experimental autoimmune encephalomyelitis (EAE) up-regulates the mitochondrial activity and manganese superoxide dismutase (MnSOD) in the mouse renal cortex

Increases of the activity of mitochondrial electron transport chain generally lead to increases of production of ATP and reactive oxygen species (ROS) as by-products. MnSOD is the first line of defense against the stress induced by mitochondrial ROS. Our previous studies demonstrated that EAE progre...

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Pubblicato in:PLoS One
Autori principali: Packialakshmi, Balamurugan, Zhou, Xiaoming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916489/
https://ncbi.nlm.nih.gov/pubmed/29689072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196277
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