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Experimental autoimmune encephalomyelitis (EAE) up-regulates the mitochondrial activity and manganese superoxide dismutase (MnSOD) in the mouse renal cortex

Increases of the activity of mitochondrial electron transport chain generally lead to increases of production of ATP and reactive oxygen species (ROS) as by-products. MnSOD is the first line of defense against the stress induced by mitochondrial ROS. Our previous studies demonstrated that EAE progre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Packialakshmi, Balamurugan, Zhou, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916489/
https://ncbi.nlm.nih.gov/pubmed/29689072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196277
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