Riluzole Impairs Cocaine Reinstatement and Restores Adaptations in Intrinsic Excitability and GLT-1 Expression

Adaptations in glutamate signaling within the brain’s reward circuitry are observed following withdrawal from several abused drugs, including cocaine. These include changes in intrinsic cellular excitability, glutamate release, and glutamate uptake. Pharmacological or optogenetic reversal of these a...

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Bibliografische gegevens
Gepubliceerd in:Neuropsychopharmacology
Hoofdauteurs: Sepulveda-Orengo, Marian T, Healey, Kati L, Kim, Ronald, Auriemma, Alyson C, Rojas, Jennifer, Woronoff, Nicholas, Hyppolite, Rachel, Reissner, Kathryn J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2018
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916346/
https://ncbi.nlm.nih.gov/pubmed/28990593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.244
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