Riluzole Impairs Cocaine Reinstatement and Restores Adaptations in Intrinsic Excitability and GLT-1 Expression

Adaptations in glutamate signaling within the brain’s reward circuitry are observed following withdrawal from several abused drugs, including cocaine. These include changes in intrinsic cellular excitability, glutamate release, and glutamate uptake. Pharmacological or optogenetic reversal of these a...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Sepulveda-Orengo, Marian T, Healey, Kati L, Kim, Ronald, Auriemma, Alyson C, Rojas, Jennifer, Woronoff, Nicholas, Hyppolite, Rachel, Reissner, Kathryn J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916346/
https://ncbi.nlm.nih.gov/pubmed/28990593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.244
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