Granulocyte-macrophage colony-stimulating factor neuroprotective activities in Alzheimer’s disease mice

We investigated the effects of granulocyte-macrophage colony stimulating factor (GM-CSF) on behavioral and pathological outcomes in Alzheimer’s disease (AD) and non-transgenic mice. GM-CSF treatment in AD mice reduced brain amyloidosis, increased plasma Aβ, and rescued cognitive impairment with incr...

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Pubblicato in:J Neuroimmunol
Autori principali: Kiyota, Tomomi, Machhi, Jatin, Lu, Yaman, Dyavarshetty, Bhagyalaxmi, Nemati, Maryam, Yokoyama, Izumi, Mosley, R. Lee, Gendelman, Howard E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916331/
https://ncbi.nlm.nih.gov/pubmed/29573847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2018.03.009
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