Nitric oxide–sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction

Heart failure with preserved ejection fraction (HFpEF) can arise from cardiac and vascular remodeling processes following long-lasting hypertension. Efficacy of common HF therapeutics is unsatisfactory in HFpEF. Evidence suggests that stimulators of the nitric oxide–sensitive soluble guanylyl cyclas...

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Publicado en:JCI Insight
Autores principales: Wilck, Nicola, Markó, Lajos, Balogh, András, Kräker, Kristin, Herse, Florian, Bartolomaeus, Hendrik, Szijártó, István A., Gollasch, Maik, Reichhart, Nadine, Strauss, Olaf, Heuser, Arnd, Brockschnieder, Damian, Kretschmer, Axel, Lesche, Ralf, Sohler, Florian, Stasch, Johannes-Peter, Sandner, Peter, Luft, Friedrich C., Müller, Dominik N., Dechend, Ralf, Haase, Nadine
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916255/
https://ncbi.nlm.nih.gov/pubmed/29467337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96006
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