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Illuminating structure and acyl donor sites of a physiological transglutaminase substrate from Streptomyces mobaraensis

Transglutaminase from Streptomyces mobaraensis (MTG) has become a powerful tool to covalently and highly specifically link functional amines to glutamine donor sites of therapeutic proteins. However, details regarding the mechanism of substrate recognition and interaction of the enzyme with proteina...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Juettner, Norbert E., Schmelz, Stefan, Bogen, Jan P., Happel, Dominic, Fessner, Wolf‐Dieter, Pfeifer, Felicitas, Fuchsbauer, Hans‐Lothar, Scrima, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916126/
https://ncbi.nlm.nih.gov/pubmed/29430769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3388
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