Improved Productivity of Streptomyces mobaraensis Transglutaminase by Regulating Zymogen Activation

Streptomyces mobaraensis transglutaminase (TGase) is extracellularly expressed as a zymogen and then activated by TGase-activating protease (TAP). In this study, we reported the strategy for improving TGase production via the regulation of TAP activity in S. mobaraensis. First, we analyzed the effec...

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Detalhes bibliográficos
Main Authors: Xiaoqiang Yin, Shengqi Rao, Jingwen Zhou, Guocheng Du, Jian Chen, Song Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
Colecção:Frontiers in Bioengineering and Biotechnology
Assuntos:
transglutaminase
Streptomyces mobaraensis
NH4+
zymogen activation
productivity
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fbioe.2022.878795/full
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