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Fused dimerization increases expression, solubility, and activity of bacterial dehydratase enzymes

FabA and FabZ are the two dehydratase enzymes in Escherichia coli that catalyze the dehydration of acyl intermediates in the biosynthesis of fatty acids. Both enzymes form obligate dimers in which the active site contains key amino acids from both subunits. While FabA is a soluble protein that has b...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Rullán‐Lind, Carlos, Pietri, Ruth B., Vázquez‐Cintrón, Melvin, Baerga‐Ortiz, Abel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916124/
https://ncbi.nlm.nih.gov/pubmed/29520922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3404
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