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The three‐dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin

The aminoglycoside antibiotics, discovered as natural products in the 1940s, demonstrate a broad antimicrobial spectrum. Due to their nephrotoxic and ototoxic side effects, however, their widespread clinical usage has typically been limited to the treatment of serious infections. Neomycin B, first i...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Protein Sci
Päätekijät: Dow, Garrett T., Thoden, James B., Holden, Hazel M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916122/
https://ncbi.nlm.nih.gov/pubmed/29516565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3400
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