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The three‐dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin

The aminoglycoside antibiotics, discovered as natural products in the 1940s, demonstrate a broad antimicrobial spectrum. Due to their nephrotoxic and ototoxic side effects, however, their widespread clinical usage has typically been limited to the treatment of serious infections. Neomycin B, first i...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Dow, Garrett T., Thoden, James B., Holden, Hazel M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916122/
https://ncbi.nlm.nih.gov/pubmed/29516565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3400
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