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Apremilast Alters Behavioral Responses to Ethanol in Mice: I. Reduced Ethanol Consumption and Preference

BACKGROUND: Phosphodiesterase type 4 (PDE4) inhibitors produce widespread anti-inflammatory effects and reduce ethanol consumption in several rodent models. These drugs are potential treatments for several diseases, including central nervous system disorders, but clinical use is limited by their eme...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Blednov, Yuri A., Da Costa, Adriana J., Tarbox, Tamara, Ponomareva, Olga, Messing, Robert O., Harris, R. Adron
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915912/
https://ncbi.nlm.nih.gov/pubmed/29469962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13616
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