Promiscuous, Multi-Target Lupane-Type Triterpenoids Inhibits Wild Type and Drug Resistant HIV-1 Replication Through the Interference With Several Targets

Current research on antiretroviral therapy is mainly focused in the development of new formulations or combinations of drugs belonging to already known targets. However, HIV-1 infection is not cured by current therapy and thus, new approaches are needed. Bevirimat was developed by chemical modificat...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Bedoya, Luis M., Beltrán, Manuela, García-Pérez, Javier, Obregón-Calderón, Patricia, Callies, Oliver, Jímenez, Ignacio A., Bazzocchi, Isabel L., Alcamí, José
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915803/
https://ncbi.nlm.nih.gov/pubmed/29720939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00358
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