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Desferrioxamine biosynthesis: diverse hydroxamate assembly by substrate-tolerant acyl transferase DesC
Hydroxamate groups play key roles in the biological function of diverse natural products. Important examples include trichostatin A, which inhibits histone deacetylases via coordination of the active site zinc(II) ion with a hydroxamate group, and the desferrioxamines, which use three hydroxamate gr...
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| Yayımlandı: | Philos Trans R Soc Lond B Biol Sci |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Royal Society
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5915712/ https://ncbi.nlm.nih.gov/pubmed/29685972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0068 |
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