AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis

Bacterial pathogens need to scavenge iron from their host for growth and proliferation during infection. They have evolved several strategies to do this, one being the biosynthesis and excretion of small, high-affinity iron chelators known as siderophores. The biosynthesis of siderophores is an impo...

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Autori principali: Schmelz, Stefan, Kadi, Nadia, McMahon, Stephen A., Song, Lijiang, Oves-Costales, Daniel, Oke, Muse, Liu, Huanting, Johnson, Kenneth A., Carter, Lester G., Botting, Catherine H., White, Malcolm F., Challis, Gregory L., Naismith, James H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644304/
https://ncbi.nlm.nih.gov/pubmed/19182782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.145
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