AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis

Bacterial pathogens need to scavenge iron from their host for growth and proliferation during infection. They have evolved several strategies to do this, one being the biosynthesis and excretion of small, high-affinity iron chelators known as siderophores. The biosynthesis of siderophores is an impo...

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Bibliographic Details
Main Authors: Schmelz, Stefan, Kadi, Nadia, McMahon, Stephen A., Song, Lijiang, Oves-Costales, Daniel, Oke, Muse, Liu, Huanting, Johnson, Kenneth A., Carter, Lester G., Botting, Catherine H., White, Malcolm F., Challis, Gregory L., Naismith, James H.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644304/
https://ncbi.nlm.nih.gov/pubmed/19182782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.145
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