Fetal demise and failed antibody therapy during Zika virus infection of pregnant macaques

Zika virus (ZIKV) infection of pregnant women is associated with pathologic complications of fetal development. Here, we infect pregnant rhesus macaques (Macaca mulatta) with a minimally passaged ZIKV isolate from Rio de Janeiro, where a high rate of fetal development complications was observed. The...

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Publicat a:Nat Commun
Autors principals: Magnani, Diogo M., Rogers, Thomas F., Maness, Nicholas J., Grubaugh, Nathan D., Beutler, Nathan, Bailey, Varian K., Gonzalez-Nieto, Lucas, Gutman, Martin J., Pedreño-Lopez, Núria, Kwal, Jaclyn M., Ricciardi, Michael J., Myers, Tereance A., Julander, Justin G., Bohm, Rudolf P., Gilbert, Margaret H., Schiro, Faith, Aye, Pyone P., Blair, Robert V., Martins, Mauricio A., Falkenstein, Kathrine P., Kaur, Amitinder, Curry, Christine L., Kallas, Esper G., Desrosiers, Ronald C., Goldschmidt-Clermont, Pascal J., Whitehead, Stephen S., Andersen, Kristian G., Bonaldo, Myrna C., Lackner, Andrew A., Panganiban, Antonito T., Burton, Dennis R., Watkins, David I.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915455/
https://ncbi.nlm.nih.gov/pubmed/29691387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04056-4
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