Alternative polyadenylation drives genome-to-phenome information detours in the AMPKα1 and AMPKα2 knockout mice

Currently available mouse knockout (KO) lines remain largely uncharacterized for genome-to-phenome (G2P) information flows. Here we test our hypothesis that altered myogenesis seen in AMPKα1- and AMPKα2-KO mice is caused by use of alternative polyadenylation sites (APSs). AMPKα1 and AMPKα2 are two α...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Zhang, Shuwen, Zhang, Yangzi, Zhou, Xiang, Fu, Xing, Michal, Jennifer J., Ji, Guoli, Du, Min, Davis, Jon F., Jiang, Zhihua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915415/
https://ncbi.nlm.nih.gov/pubmed/29691479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24683-7
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi