Characterization of a new B-ALL cell line with constitutional defect of the Notch signaling pathway

Notch signaling contribution to B-cell acute lymphoblastic leukemia (B-ALL) development is still under investigation. The serendipitous onset of B-ALL in a patient affected by the germinal Notch mutation-dependent Alagille syndrome allowed us to establish a B-ALL cell line (VR-ALL) bearing a genetic...

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Publicat a:Oncotarget
Autors principals: Kamga, Paul Takam, Dal Collo, Giada, Bassi, Giulio, Midolo, Martina, Delledonne, Massimo, Chilosi, Marco, Bonifacio, Massimiliano, Krampera, Mauro
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915076/
https://ncbi.nlm.nih.gov/pubmed/29719609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24836
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