Notch signalling drives bone marrow stromal cell-mediated chemoresistance in acute myeloid leukemia

Both preclinical and clinical investigations suggest that Notch signalling is critical for the development of many cancers and for their response to chemotherapy. We previously showed that Notch inhibition abrogates stromal-induced chemoresistance in lymphoid neoplasms. However, the role of Notch in...

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Vydáno v:Oncotarget
Hlavní autoři: Kamga, Paul Takam, Bassi, Giulio, Cassaro, Adriana, Midolo, Martina, Di Trapani, Mariano, Gatti, Alessandro, Carusone, Roberta, Resci, Federica, Perbellini, Omar, Gottardi, Michele, Bonifacio, Massimiliano, Kamdje, Armel Hervé Nwabo, Ambrosetti, Achille, Krampera, Mauro
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008317/
https://ncbi.nlm.nih.gov/pubmed/26967055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7964
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