Endonuclease G promotes mitochondrial genome cleavage and replication

Endonuclease G (EndoG) is a nuclear-encoded endonuclease, mostly localised in mitochondria. In the nucleus EndoG participates in site-specific cleavage during replication stress and genome-wide DNA degradation during apoptosis. However, the impact of EndoG on mitochondrial DNA (mtDNA) metabolism is...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Wiehe, Rahel Stefanie, Gole, Boris, Chatre, Laurent, Walther, Paul, Calzia, Enrico, Ricchetti, Miria, Wiesmüller, Lisa
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2018
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915074/
https://ncbi.nlm.nih.gov/pubmed/29719607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24822
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki