2’-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer

Breast cancer (BC) is the most common cancer in women. Estrogen, epidermal growth factor receptor 2 (ERBB2, HER2), and oxidative stress represent critical mechanistic nodes associated with BC. RLIP76 is a major mercapturic acid pathway transporter whose expression is increased in BC. In the quest of...

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Publicado en:Oncotarget
Autores principales: Nagaprashantha, Lokesh Dalasanur, Singhal, Jyotsana, Li, Hongzhi, Warden, Charles, Liu, Xueli, Horne, David, Awasthi, Sanjay, Salgia, Ravi, Singhal, Sharad S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915057/
https://ncbi.nlm.nih.gov/pubmed/29719590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24720
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