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Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands

Pseudomonas aeruginosa is an opportunistic pathogen that uses the process of quorum sensing (QS) to coordinate the expression of many virulence genes. During quorum sensing, N-acyl-homoserine lactone (AHL) signaling molecules regulate the activity of three LuxR-type transcription factors, LasR, RhlR...

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Publicado en:Mol Microbiol
Autores principales: Wysoczynski-Horita, Christina L., Boursier, Michelle E., Hill, Ryan, Hansen, Kirk, Blackwell, Helen E., Churchill, Mair E. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914528/
https://ncbi.nlm.nih.gov/pubmed/29437248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13930
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