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Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands

Pseudomonas aeruginosa is an opportunistic pathogen that uses the process of quorum sensing (QS) to coordinate the expression of many virulence genes. During quorum sensing, N-acyl-homoserine lactone (AHL) signaling molecules regulate the activity of three LuxR-type transcription factors, LasR, RhlR...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Microbiol
Prif Awduron: Wysoczynski-Horita, Christina L., Boursier, Michelle E., Hill, Ryan, Hansen, Kirk, Blackwell, Helen E., Churchill, Mair E. A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914528/
https://ncbi.nlm.nih.gov/pubmed/29437248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13930
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