Oral Abuse Potential, Pharmacokinetics, and Safety of Once-Daily, Single-Entity, Extended-Release Hydrocodone (HYD) in Recreational Opioid Users

Objectives. A once-daily, extended-release hydrocodone bitartrate tablet with abuse-deterrent properties (Hysingla ER [HYD]) is available for the treatment of chronic pain in appropriate patients. This study evaluated the oral abuse potential and pharmacokinetics (PK) of HYD intact, chewed, or mille...

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Publicat a:Pain Med
Autors principals: Harris, Stephen C., Cipriano, Alessandra, Colucci, Salvatore V., Kapil, Ram P., Geoffroy, Pierre, Hopyan, Talar, Levy-Cooperman, Naama
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
OPIOIDS, SUBSTANCE ABUSE & ADDICTIONS SECTION
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914330/
https://ncbi.nlm.nih.gov/pubmed/27651514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/pm/pnw208
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