Mass and charge distributions of amyloid fibers involved in neurodegenerative diseases: mapping heterogeneity and polymorphism

Heterogeneity and polymorphism are generic features of amyloid fibers with some important effects on the related disease development. We report here the characterization, by charge detection mass spectrometry, of amyloid fibers made of three polypeptides involved in neurodegenerative diseases: Aβ(1–...

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Bibliografische gegevens
Gepubliceerd in:Chem Sci
Hoofdauteurs: Pansieri, Jonathan, Halim, Mohammad A., Vendrely, Charlotte, Dumoulin, Mireille, Legrand, François, Sallanon, Marcelle Moulin, Chierici, Sabine, Denti, Simona, Dagany, Xavier, Dugourd, Philippe, Marquette, Christel, Antoine, Rodolphe, Forge, Vincent
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Royal Society of Chemistry 2018
Onderwerpen:
Chemistry
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914292/
https://ncbi.nlm.nih.gov/pubmed/29732065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04542e
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