Mass and charge distributions of amyloid fibers involved in neurodegenerative diseases: mapping heterogeneity and polymorphism

Heterogeneity and polymorphism are generic features of amyloid fibers with some important effects on the related disease development. We report here the characterization, by charge detection mass spectrometry, of amyloid fibers made of three polypeptides involved in neurodegenerative diseases: Aβ(1–...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Pansieri, Jonathan, Halim, Mohammad A., Vendrely, Charlotte, Dumoulin, Mireille, Legrand, François, Sallanon, Marcelle Moulin, Chierici, Sabine, Denti, Simona, Dagany, Xavier, Dugourd, Philippe, Marquette, Christel, Antoine, Rodolphe, Forge, Vincent
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2018
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914292/
https://ncbi.nlm.nih.gov/pubmed/29732065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04542e
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