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Population Pharmacokinetics of Cefotaxime and Dosage Recommendations in Children with Sickle Cell Disease

The pharmacokinetic profile of most drugs is dependent on the patient's covariates and may be influenced by the disease. Cefotaxime is frequently prescribed in pediatric patients with sickle cell disease (SCD), characterized by vaso-occlusive complications, chronic hemolytic anemia, and a defec...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Maksoud, Elsa, Koehl, Berengere, Facchin, Aude, Ha, Phuong, Zhao, Wei, Kaguelidou, Florentia, Benkerrou, Malika, Mariani, Patricia, Faye, Albert, Lorrot, Mathie, Jacqz-Aigrain, Evelyne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914001/
https://ncbi.nlm.nih.gov/pubmed/29378711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00637-17
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