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Population Pharmacokinetics of Cefotaxime and Dosage Recommendations in Children with Sickle Cell Disease

The pharmacokinetic profile of most drugs is dependent on the patient's covariates and may be influenced by the disease. Cefotaxime is frequently prescribed in pediatric patients with sickle cell disease (SCD), characterized by vaso-occlusive complications, chronic hemolytic anemia, and a defec...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Maksoud, Elsa, Koehl, Berengere, Facchin, Aude, Ha, Phuong, Zhao, Wei, Kaguelidou, Florentia, Benkerrou, Malika, Mariani, Patricia, Faye, Albert, Lorrot, Mathie, Jacqz-Aigrain, Evelyne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914001/
https://ncbi.nlm.nih.gov/pubmed/29378711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00637-17
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