Emergence of Resistance to Colistin During the Treatment of Bloodstream Infection Caused by Klebsiella pneumoniae Carbapenemase–Producing Klebsiella pneumoniae

We report the emergence of colistin resistance in Klebsiella pneumoniae carbapenemase (KPC)–producing Klebsiella pneumoniae after 8 days of colistin-based therapy, resulting in relapse of bloodstream infection and death. Disruption of the mgrB gene by insertion of a mobile genetic element was found...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Kanwar, Anubhav, Marshall, Steven H, Perez, Federico, Tomas, Myreen, Jacobs, Michael R, Hujer, Andrea M, Domitrovic, T Nicholas, Rudin, Susan D, Rojas, Laura J, Kreiswirth, Barry N, Chen, Liang, Quinones-Mateu, Miguel, van Duin, David, Bonomo, Robert A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913667/
https://ncbi.nlm.nih.gov/pubmed/30014001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy054
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