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Genomic and Transcriptomic Analyses of Colistin-Resistant Clinical Isolates of Klebsiella pneumoniae Reveal Multiple Pathways of Resistance

The emergence of multidrug-resistant (MDR) Klebsiella pneumoniae has resulted in a more frequent reliance on treatment using colistin. However, resistance to colistin (Col(r)) is increasingly reported from clinical settings. The genetic mechanisms that lead to Col(r) in K. pneumoniae are not fully c...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Wright, Meredith S., Suzuki, Yo, Jones, Marcus B., Marshall, Steven H., Rudin, Susan D., van Duin, David, Kaye, Keith, Jacobs, Michael R., Bonomo, Robert A., Adams, Mark D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291396/
https://ncbi.nlm.nih.gov/pubmed/25385117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04037-14
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