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Genomic and Transcriptomic Analyses of Colistin-Resistant Clinical Isolates of Klebsiella pneumoniae Reveal Multiple Pathways of Resistance

The emergence of multidrug-resistant (MDR) Klebsiella pneumoniae has resulted in a more frequent reliance on treatment using colistin. However, resistance to colistin (Col(r)) is increasingly reported from clinical settings. The genetic mechanisms that lead to Col(r) in K. pneumoniae are not fully c...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wright, Meredith S., Suzuki, Yo, Jones, Marcus B., Marshall, Steven H., Rudin, Susan D., van Duin, David, Kaye, Keith, Jacobs, Michael R., Bonomo, Robert A., Adams, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291396/
https://ncbi.nlm.nih.gov/pubmed/25385117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04037-14
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