Niclosamide inhibits vascular smooth muscle cell proliferation and migration and attenuates neointimal hyperplasia in injured rat carotid arteries

BACKGROUND AND PURPOSE: The anti‐helminthic drug niclosamide regulates multiple cellular signals including STAT3, AMP‐activated protein kinase (AMPK), Akt, Wnt/β‐catenin and mitochondrial uncoupling which are involved in neointimal hyperplasia. Here we have examined the effects of niclosamide on vas...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Xiao, Xiao‐Lin, Hu, Nan, Zhang, Xin‐Zi, Jiang, Man, Chen, Chang, Ma, Rui, Ma, Zhen‐Gang, Gao, Jin‐Lai, Xuan, Xiu‐Chen, Sun, Zhi‐Jie, Dong, De‐Li
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913402/
https://ncbi.nlm.nih.gov/pubmed/29486057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14182
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