Valproic Acid Attenuates Traumatic Brain Injury-Induced Inflammation in Vivo: Involvement of Autophagy and the Nrf2/ARE Signaling Pathway

Microglial activation and the inflammatory response in the central nervous system (CNS) play important roles in secondary damage after traumatic brain injury (TBI). Transcriptional activation of genes that limit secondary damage to the CNS are mediated by a cis-acting element called the antioxidant...

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Pubblicato in:Front Mol Neurosci
Autori principali: Chen, Xiangrong, Wang, Handong, Zhou, Mengliang, Li, Xiang, Fang, Zhongning, Gao, Hongzhi, Li, Yasong, Hu, Weipeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913341/
https://ncbi.nlm.nih.gov/pubmed/29719500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00117
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