Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis

Necroptosis, a regulated necrosis pathway mediated by the receptor-interacting protein kinases 1 and 3 (RIPK1 and RIPK3), is induced following spinal cord injury (SCI) and thought to contribute to neuronal and glial cell death. However, mechanisms leading to activation of necroptosis after SCI remai...

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Bibliografiska uppgifter
I publikationen:Cell Death Dis
Huvudupphovsmän: Liu, Shuo, Li, Yun, Choi, Harry M. C., Sarkar, Chinmoy, Koh, Eugene Y., Wu, Junfang, Lipinski, Marta M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913300/
https://ncbi.nlm.nih.gov/pubmed/29686269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0469-1
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