Complement Factor H-Related Protein 4A Is the Dominant Circulating Splice Variant of CFHR4

Recent research has elucidated circulating levels of almost all factor H-related (FHR) proteins. Some of these proteins are hypothesized to act as antagonists of the important complement regulator factor H (FH), fine-tuning complement regulation on human surfaces. For the CFHR4 splice variants FHR-4...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Pouw, Richard B., Brouwer, Mieke C., van Beek, Anna E., Józsi, Mihály, Wouters, Diana, Kuijpers, Taco W.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913293/
https://ncbi.nlm.nih.gov/pubmed/29719534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00729
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